2',5-Difluoro-2'-deoxy-1-arabinosyluracil
5-Fluoro-1- ((2R,3S,4R,5R) -3-fluoro-4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyrimidine-2,4 (1H,3H) -dione (2',5-difluoro-2'-deoxy-1-arabinosyluracil) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Product Specifications
CAS Number
[69123-95-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-5-difluoro-2-deoxy-1-arabinosyluracil.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](F)[C@H](N2C(NC(C(F)=C2)=O)=O)O[C@@H]1CO.C
Molecular Formula
C10H14F2N2O5
Molecular Weight
280.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20 (5) :218-25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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