PRTN3, Human (S203A, HEK293, His)

PRTN3 is a serine protease that broadly targets elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV in vitro, playing a crucial role in extracellular matrix degradation. It modulates endothelial cell barrier function by cleaving and activating the receptor F2RL1/PAR-2 and enhances vascular integrity during neutrophil transendothelial migration. PRTN3 Protein, Human (S203A, HEK293, His) is the recombinant human-derived PRTN3 protein, expressed by HEK293 , with C-His labeled tag and I28-P256, , , , mutation. The total length of PRTN3 Protein, Human (S203A, HEK293, His) is 229 a.a., with molecular weight of ~26.57 kDa.