Leukotriene D4

Leukotriene D4 is a potent bronchoconstrictor. Leukotriene D4 has the potential for the research of asthma. Leukotriene D4 induces edema and increases capillary permeability[1][2].

Product Specifications

CAS Number

[73836-78-9]

Product Name Alternative

NVS-MELK8a (hydrochloride)

UNSPSC

12352211

Hazard Statement

H225, H301+H311+H331, H370

Target

Drug Metabolite; Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/leukotriene-d4.html

Concentration

201.34 μM * 100 μL in Ethanol

Purity

98.5

Solubility

10 mM in DMSO

Smiles

O=C(O)CNC([C@H](CS[C@@H]([C@@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCCC)N)=O

Molecular Formula

C25H40N2O6S

Molecular Weight

496.66

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Smith LJ, et al. The effect of inhaled leukotriene D4 in humans. Am Rev Respir Dis. 1985 Mar;131 (3) :368-72.|[2]Griswold DE, et al. Phlogistic activity of leukotriene D4 in the mouse. Inflammation. 1986 Mar;10 (1) :1-7.