11-Deoxy-11-methylene PGD2

11-Deoxy-11-methylene PGD2 (11d-11m-PGD2) is a chemically stable, isosteric analogue of Prostaglandin 2 in which the 11-keto group is replaced by an exocyclic methylene. 11-Deoxy-11-methylene PGD2 is significantly stimulating the storage of fats suppressed in the presence of Indomethacin[1].

Product Specifications

CAS Number

[100648-29-1]

Product Name Alternative

11d-11m-PGD2; 11-Deoxy-11-Methylene prostaglandin D2

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/11-deoxy-11-methylene-pgd2.html

Solubility

10 mM in DMSO

Smiles

OC(CCC/C=C\C[C@@H]1[C@H](C(C[C@@H]1O)=C)/C=C/[C@@H](O)CCCCC)=O

Molecular Formula

C21H34O4

Molecular Weight

350.49

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Mohammad Shahidur Rahman, et al. Comparison of pro-adipogenic effects between prostaglandin (PG) D2 and its stable, isosteric analogue, 11-deoxy-11-methylene-PGD2, during the maturation phase of cultured adipocytes. Prostaglandins Other Lipid Mediat. 2018 Nov:139:71-79.