What is the catalog number for Galidesivir?

The catalog number for Galidesivir is HY-18649A.

What sizes are available for Galidesivir?

Galidesivir is available in the following size(s): 1 mg, 5 mg, 10 mg.

How many pack sizes does Galidesivir come in?

Galidesivir is available in 3 different pack sizes.

Is Galidesivir in stock?

Galidesivir is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Galidesivir?

Galidesivir is manufactured by QuantiMol.

What is the estimated delivery time for Galidesivir?

Estimated delivery time for Galidesivir is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Galidesivir?

The safety data sheet for Galidesivir is available here: http://file.medchemexpress.com/batch_PDF/HY-18649A/Galidesivir-SDS-MedChemExpress.pdf.

Galidesivir

Galidesivir (BCX4430), an adenosine analog and a direct-acting antiviral agent, disrupts viral RNA-dependent RNA polymerase (RdRp) activity. Galidesivir is active in vitro against many RNA viral pathogens, including the filoviruses and emerging infectious agents such as MERS-CoV, SARS-CoV, and SARS-CoV-2. Galidesivir inhibits some negative-sense RNA viruses with EC50s ranging from ~3 to ~68 μM[1][2][3].

Product Specifications

CAS Number

249503-25-1

Product Name Alternative

BCX4430; Immucillin-A

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

DNA/RNA Synthesis; Filovirus; SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/BCX4430-freebase.html

Purity

99.29

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](C2=CNC3=C2N=CN=C3N)N[C@H](CO)[C@H]1O

Molecular Formula

C11H15N5O3

Molecular Weight

265.27

Precautions

H302, H315, H319

References & Citations

[1]Elfiky AA, et al. ICN-1229, Remdesivir, PSI-7977, Galidesivir, and GS 1278 against SARS-CoV-2 RNA dependent RNA polymerase (RdRp) : A molecular docking study. Life Sci. 2020 Mar 25:117592.|[2]Taylor R, et al. BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease. J Infect Public Health. 2016;9 (3) :220-226.|[3]Warren TK, et al. Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430. Nature. 2014;508 (7496) :402-405.|[4]Julander JG, et al. BCX4430, a novel nucleoside analog, effectively treats yellow fever in a Hamster model. Antimicrob Agents Chemother. 2014;58 (11) :6607-6614.