Human a-Synuclein Conjugated to Fluor 488

<strong>Human a-Synuclein Conjugated to Fluor 488</strong>_x000D_ <strong>Catalog number:</strong> B2011445_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 200 µL_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80 ¬∞C_x000D_ <strong>Keywords:</strong> Human recombinant alpha-Synuclein (1-140), HiLyte‚Ñ¢ Fluor 488 labeled_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Marogianni C, Sokratous M, Dardiotis E, Hadjigeorgiou GM, Bogdanos D, Xiromerisiou G. Neurodegeneration and Inflammation-An Interesting Interplay in Parkinson's Disease Int J Mol Sci. 2020 Nov 10;21(22):8421._x000D_ 2: Stefani A, Iranzo A, Holzknecht E, Perra D, Bongianni M, Gaig C, Heim B, Serradell M, Sacchetto L, Garrido A, Capaldi S, S√°nchez-G√≥mez A, Cecchini MP, Mariotto S, Ferrari S, Fiorini M, Schmutzhard J, Cocchiara P, Vilaseca I, Brozzetti L, Monaco S, Jose Marti M, Seppi K, Tolosa E, Santamaria J, H√∂gl B, Poewe W, Zanusso G; SINBAR (Sleep Innsbruck Barcelona) group. Alpha-synuclein seeds in olfactory mucosa of patients with isolated REM sleep behaviour disorder Brain. 2021 May 7;144(4):1118-1126._x000D_ 3: Badanjak K, Fixemer S, Smajiƒá S, Skupin A, Gr√ºnewald A. The Contribution of Microglia to Neuroinflammation in Parkinson's Disease Int J Mol Sci. 2021 Apr 28;22(9):4676._x000D_ 4: Guiney SJ, Adlard PA, Lei P, Mawal CH, Bush AI, Finkelstein DI, Ayton S. Fibrillar Œ±-synuclein toxicity depends on functional lysosomes J Biol Chem. 2020 Dec 18;295(51):17497-17513._x000D_ 5: Kim GJ, Mo H, Liu H, Wu Z, Chen S, Zheng J, Zhao X, Nucum D, Shortland J, Peng L, Elepano M, Tang B, Olson S, Paras N, Li H, Renslo AR, Arkin MR, Huang B, Lu B, Sirota M, Guo S. A zebrafish screen reveals Renin-angiotensin system inhibitors as neuroprotective via mitochondrial restoration in dopamine neurons Elife. 2021 Sep 22;10:e69795._x000D_ 6: Yamashita S, O Kamatari Y, Honda R, Niwa A, Tomiata H, Hara A, Kuwata K. Monomeric a-synuclein (aS) inhibits amyloidogenesis of human prion protein (hPrP) by forming a stable aS-hPrP hetero-dimer Prion. 2021 Dec;15(1):37-43._x000D_ 7: Qiao H, He X, Zhang Q, Yuan H, Wang D, Li L, Hui Y, Wu Z, Li W, Zhang N. Alpha-synuclein induces microglial migration via PKM2-dependent glycolysis Int J Biol Macromol. 2019 May 15;129:601-607._x000D_ 8: Blumenstock S, Sun F, Klaus C, Marinkoviƒá P, Sgobio C, Paeger L, Liebscher S, Herms J. Cortical circuit dysfunction in a mouse model of alpha-synucleinopathy in vivo Brain Commun. 2021 Nov 15;3(4):fcab273._x000D_ 9: Han JY, Jang HS, Green AJE, Choi YP. RT-QuIC-based detection of alpha-synuclein seeding activity in brains of dementia with Lewy Body patients and of a transgenic mouse model of synucleinopathy Prion. 2020 Dec;14(1):88-94._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/23225002">10: Paleologou KE, El-Agnaf OM. Œ±-Synuclein aggregation and modulating factors Subcell Biochem. 2012;65:109-64. </a>_x000D_ _x000D_ <strong>Products Related to Human a-Synuclein Conjugated to Fluor 488 can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>