PU-WS13
PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.
Product Specifications
CAS Number
[1454619-14-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PU-WS13.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : ≥ 40 mg/mL
Smiles
CC(NCCCN1C(SC2=CC(Cl)=CC(Cl)=C2)=NC3=C(N)N=CN=C13)C
Molecular Formula
C17H20Cl2N6S
Molecular Weight
411.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Patel PD, et al. Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol. 2013 Nov;9 (11) :677-684.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90
Available Sizes
Curated Selection
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