5-Methylcytosine dNTP Mix

<strong>5-Methylcytosine dNTP Mix</strong>_x000D_ <strong>Catalog number:</strong> B2016637_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 uL _x000D_ <strong>Molecular Weight or Concentration:</strong> 10 mM_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> 5-Methylcytosine dNTP Mix_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong> _x000D_ 1: Pospíšil Š, Panattoni A, Gracias F, Sýkorová V, Hausnerová VV, Vítovská D, Šanderová H, Krásný L, Hocek M. Epigenetic Pyrimidine Nucleotides in Competition with Natural dNTPs as Substrates for Diverse DNA Polymerases ACS Chem Biol. 2022 Oct 21;17(10):2781-2788. _x000D_ 2: Puchtler TJ, Johnson K, Palmer RN, Talbot EL, Ibbotson LA, Powalowska PK, Knox R, Shibahara A, M S Cunha P, Newell OJ, Wu M, Chana J, Athanasopoulou EN, Waeber AM, Stolarek M, Silva AL, Mordaka JM, Haggis-Powell M, Xyrafaki C, Bush J, Topkaya IS, Sosna M, Ingham RJ, Huckvale T, Negrea A, Breiner B, Šlikas J, Kelly DJ, Dunning AJ, Bell NM, Dethlefsen M, Love DM, Dear PH, Kuleshova J, Podd GJ, Isaac TH, Balmforth BW, Frayling CA. Single-molecule DNA sequencing of widely varying GC-content using nucleotide release, capture and detection in microdroplets Nucleic Acids Res. 2020 Dec 16;48(22):e132. _x000D_ 3: Boháčová S, Vaníková Z, Poštová Slavětínská L, Hocek M. Protected 2'-deoxyribonucleoside triphosphate building blocks for the photocaging of epigenetic 5-(hydroxymethyl)cytosine in DNA Org Biomol Chem. 2018 Aug 1;16(30):5427-5432. _x000D_ 4: Kukhanova M, Lin ZY, Yas'co M, Cheng YC. Unique inhibitory effect of 1-(2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)-5-methyluracil 5'-triphosphate on Epstein-Barr virus and human DNA polymerases Biochem Pharmacol. 1998 Apr 15;55(8):1181-7. _x000D_ 5: Wnuk M, Slipek P, Dziedzic M, Lewinska A. The Roles of Host 5-Methylcytosine RNA Methyltransferases during Viral Infections Int J Mol Sci. 2020 Oct 31;21(21):8176. _x000D_ 6: Zhang Q, Liu F, Chen W, Miao H, Liang H, Liao Z, Zhang Z, Zhang B. The role of RNA m(5)C modification in cancer metastasis Int J Biol Sci. 2021 Aug 2;17(13):3369-3380. _x000D_ 7: Taryma-Lesniak O, Sokolowska KE, Wojdacz TK. Short history of 5-methylcytosine: from discovery to clinical applications J Clin Pathol. 2021 Nov;74(11):692-696. _x000D_ 8: Muñoz-López Á, Summerer D. Recognition of Oxidized 5-Methylcytosine Derivatives in DNA by Natural and Engineered Protein Scaffolds Chem Rec. 2018 Jan;18(1):105-116. _x000D_ 9: Cadet J, Wagner JR. TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine Mutat Res Genet Toxicol Environ Mutagen. 2014 Apr;764-765:18-35. _x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20007150">10: Motorin Y, Lyko F, Helm M. 5-methylcytosine in RNA: detection, enzymatic formation and biological functions Nucleic Acids Res. 2010 Mar;38(5):1415-30. </a>_x000D_ <br><strong>Products Related to 5-Methylcytosine dNTP Mix can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>