Isozaluzanin C

Isozaluzanin C (Dehydrozaluzanin c-derivative) is an anti-inflammatory agent that can be isolated from Saussurea lappa and has immunomodulatory effects. Isozaluzanin C improves tissue damage (lung, kidney, and liver) and excessive inflammation in mice induced by LPS (HY-D1056) or CRKP infection. Isozaluzanin C can be used in the study of bacterial infections and sepsi[1][2].

Product Specifications

CAS Number

[67667-64-5]

Product Name Alternative

Dehydrozaluzanin C-derivative

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isozaluzanin-c.html

Purity

96.18

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(O[C@@]([C@@]1([H])C([C@H](O)C[C@@]21[H])=C)([H])[C@@]3([H])CCC2=C)C3=C

Molecular Formula

C15H18O3

Molecular Weight

246.30

References & Citations

[1]Kalsi S, et al. Isodehydrocostus lactone and isozaluzanin C, two guaianolides from Saussurea lappa[J]. Phytochemistry, 1983, 22 (9) : 1993-1995.|[2]Zou, et al. Dehydrozaluzanin C-derivative protects septic mice by alleviating over-activated inflammatory response and promotes the phagocytosis of macrophages[J]. bioRxiv, 2023: 2023.11. 01.565192.