PI5P4Kγ-IN-1

PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells[1].

Product Specifications

CAS Number

[2419358-87-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

PI5P4K

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pi5p4kγ-in-1.html

Purity

98.82

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=NC(C2=C(CCC3)NC4=C2C=C(C5=CCOCC5)C=C4)=C3C=N1

Molecular Formula

C20H20N4O

Molecular Weight

332.40

Precautions

H315, H319, H320

References & Citations

[1]Drewry D H, et al. Identification of a chemical probe for lipid kinase phosphatidylinositol-5-phosphate 4-kinase gamma (PI5P4K) [J]. Current Research in Chemical Biology, 2023, 3: 100036.