PI5P4Kγ-IN-1
PI5P4Kγ-IN-1 (compound 2) is a selective PI5P4Kγ inhibitor. PI5P4Kγ-IN-1 can be used to signal mTORC1 in MCF-7 breast cancer cells and further characterize PI5P4Kγ in the cells[1].
Product Specifications
CAS Number
[2419358-87-3]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
PI5P4K
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi5p4kγ-in-1.html
Purity
98.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NC1=NC(C2=C(CCC3)NC4=C2C=C(C5=CCOCC5)C=C4)=C3C=N1
Molecular Formula
C20H20N4O
Molecular Weight
332.40
Precautions
H315, H319, H320
References & Citations
[1]Drewry D H, et al. Identification of a chemical probe for lipid kinase phosphatidylinositol-5-phosphate 4-kinase gamma (PI5P4K) [J]. Current Research in Chemical Biology, 2023, 3: 100036.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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