Isoglycycoumarin
Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6) [1][2].
Product Specifications
CAS Number
117038-82-1
UNSPSC
12352005
Target
Cytochrome P450
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/isoglycycoumarin.html
Solubility
10 mM in DMSO
Smiles
COC1=C(CCC(C)(C)O2)C2=CC(O3)=C1C=C(C4=C(C=C(O)C=C4)O)C3=O
Molecular Formula
C21H20O6
Molecular Weight
368.38
References & Citations
[1]Li S, et al. Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities. Bioorg Med Chem Lett. 2010 Sep 15;20 (18) :5398-401.|[2]Wang Q, et al. The prenylated phenolic natural product isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6. Eur J Pharm Sci. 2017 Nov 15;109:472-479.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CYP2
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