TAS2R14 agonist-2
Product Specifications
UNSPSC Description
TAS2R14 agonist-2 (compound 28.1) is a potent and selective TAS2R14 inhibitor with an EC50 value of 72 nM[1].
Target Antigen
Taste Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tas2r14-agonist-2.html
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
FC(F)(C1=CC(C)=NC(NC2=C(C3=NN=NN3)C=CC=C2)=N1)F
Molecular Weight
321.26
References & Citations
[1]Waterloo L, et al. Discovery of 2-Aminopyrimidines as Potent Agonists for the Bitter Taste Receptor TAS2R14. J Med Chem. 2023 Mar 9;66(5):3499-3521.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153265/TAS2R14-agonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153265/TAS2R14-agonist-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2883007-69-8
Available Sizes
Curated Selection
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