Alpha-1-Antitrypsin Antibody / AAT / SERPINA1
It recognizes a protein of 54kDa, which is identified antitrypsin (AAT) . The immunohistochemical staining of AAT is useful in identification of benign and malignant hepatic tumors and yolk sac carcinomas. Positive staining for AAT is also used in detection of benign and malignant lesions of histiocytic nature. This antibody is may also useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with fibrosis of uncertain origin.
Product Specifications
UniProt
P01009
Reactivity
Human
Immunogen
A recombinant human Alpha-1-Antitrypsin (AAT) protein fragment was used as the immunogen for the Alpha-1-Antitrypsin antibody.
Clonality
Monoclonal
Clone
AAT/4609
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT, Western blot: 2-4ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Alpha-1-Antitrypsin antibody should be determined by the researcher.
Tested Applications
IHC-P, WB
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG
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