Syk Kinase Peptide Substrate

<strong>Syk Kinase Peptide Substrate</strong>_x000D_ <strong>Catalog number:</strong> B2011502_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1463.6 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> Syk Kinase Peptide System_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lipchik AM, Killins RL, Geahlen RL, Parker LL. A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition Biochemistry. 2012 Sep 25;51(38):7515-24._x000D_ 2: Uckun FM, Qazi S, Ma H, Tuel-Ahlgren L, Ozer Z. STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2902-7._x000D_ 3: Kim JY, Huh K, Jung R, Kim TJ. Identification of BCAR-1 as a new substrate of Syk tyrosine kinase through a determination of amino acid sequence preferences surrounding the substrate tyrosine residue Immunol Lett. 2011 Mar 30;135(1-2):151-7._x000D_ 4: Yamamoto N, Hasegawa H, Seki H, Ziegelbauer K, Yasuda T. Development of a high-throughput fluoroimmunoassay for Syk kinase and Syk kinase inhibitors Anal Biochem. 2003 Apr 15;315(2):256-61._x000D_ 5: Yi YS, Kim HG, Kim JH, Yang WS, Kim E, Jeong D, Park JG, Aziz N, Kim S, Parameswaran N, Cho JY. Syk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages Front Immunol. 2021 Dec 23;12:767366._x000D_ 6: Yu S, Huang H, Iliuk A, Wang WH, Jayasundera KB, Tao WA, Post CB, Geahlen RL. Syk inhibits the activity of protein kinase A by phosphorylating tyrosine 330 of the catalytic subunit J Biol Chem. 2013 Apr 12;288(15):10870-81._x000D_ 7: de Castro RO, Zhang J, Jamur MC, Oliver C, Siraganian RP. Tyrosines in the carboxyl terminus regulate Syk kinase activity and function J Biol Chem. 2010 Aug 20;285(34):26674-84._x000D_ 8: Kulathu Y, Hobeika E, Turchinovich G, Reth M. The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development EMBO J. 2008 May 7;27(9):1333-44._x000D_ 9: Lau C, Wang X, Song L, North M, Wiehler S, Proud D, Chow CW. Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization J Immunol. 2008 Jan 15;180(2):870-80._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/19909371">10: Kulathu Y, Grothe G, Reth M. Autoinhibition and adapter function of Syk Immunol Rev. 2009 Nov;232(1):286-99. </a>_x000D_ _x000D_ <strong>Products Related to Syk Kinase Peptide Substrate can be found at</strong> <a href="https://moleculardepot.com/product-category/Substrates/"> Substrates</a>