MK 319
MK 319 is a selective aldose reductase (AR) inhibitor with an IC50 of 0.3 μM. MK 319 can be utilized in diabetes research[1].
Product Specifications
CAS Number
1462383-00-1
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mk-319.html
Smiles
O=C(C1=CC=C(C=C1OCC(O)=O)Cl)NCC2=C(C(F)=C(C(F)=C2F)Br)F
Molecular Formula
C16H9BrClF4NO4
Molecular Weight
470.60
References & Citations
[1]Cousido-Siah A, et al. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. ACS Chem Biol. 2016 Oct 21;11 (10) :2693-2705.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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