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Amino-PEG11-amine

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES) -based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].

Product Specifications

CAS Number

479200-82-3

UNSPSC

12352211

Hazard Statement

H315, H319

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/amino-peg11-amine.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Molecular Formula

C24H52N2O11

Molecular Weight

544.68

Precautions

H315, H319

References & Citations

[1]Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8 (4) :707-15.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PEG Linkers

Available Sizes

Frequently Asked Questions

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