CEBPZ Antibody
C/EBPZ (CCAAT/enhancer-binding protein Z), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBPZ stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBPZ is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBPZ promoter may be involved with acute myeloid leukemia. The C/EBPZ gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2.
Product Specifications
UniProt
Q03701
Reactivity
Human
Immunogen
The protein domain of CEBPZ protein was used as the immunogen for the CEBPZ antibody.
Clonality
Monoclonal
Clone
PCRP-CEBPZ-2D8
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Protein A/G affinity
Dilution
Flow cytometry: 1-2ug/million cells, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CEBPZ antibody should be determined by the researcher.
Tested Applications
FACS, IHC-P
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2c
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Anti-Glycogen synthase 1/GYS1 Antibody Picoband® Fluoro550 Conjugated
