FOXL2 Antibody / Forkhead box protein L2
FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.
Product Specifications
UniProt
P58012
Reactivity
Human
Immunogen
The protein domain of FOXL2 protein was used as the immunogen for the FOXL2 antibody.
Clonality
Monoclonal
Clone
PCRP-FOXL2-1B4
Conjugation
Unconjugated
Field of Research
Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
ELISA (Order BSA-free format for coating), Flow cytometry: 1-2ug/million cells
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the FOXL2 antibody should be determined by the researcher.
Tested Applications
ELISA, FACS
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG2c
Available Sizes
Frequently Asked Questions
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