IGF2BP2 Antibody / IMP-2
IGF2BP2 (Insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type two diabetes mellitus.
Product Specifications
UniProt
Q9Y6M1
Reactivity
Human
Immunogen
Recombinant full-length human IGF2BP2 protein was used as the immunogen for the IGF2BP2 antibody.
Clonality
Monoclonal
Clone
PCRP-IGF2BP2-1F9
Conjugation
Unconjugated
Purification
Protein A/G affinity
Dilution
Flow cytometry: 1-2ug/million cells
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the IGF2BP2 antibody should be determined by the researcher.
Tested Applications
FACS
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG2, kappa
Available Sizes
Frequently Asked Questions
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