AK-778-XXMU
Product Specifications
UNSPSC Description
AK-778-XXMU is a potent inhibitor of DNA Binding 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down the tumor growth[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ak-778-xxmu.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CC=N1)CC2(C(N(C3=C2C=CC=C3)CC4=CC=CC(Cl)=C4)=O)O
Molecular Weight
392.83
References & Citations
[1]Zhong G, et al. Discovery of novel ID2 antagonists from pharmacophore-based virtual screening as potential therapeutics for glioma. Bioorg Med Chem. 2021;49:116427.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144707/AK-778-XXMU-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144707/AK-778-XXMU-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1227045-76-2
Available Sizes
Curated Selection
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