Paired-like homeobox 2B Antibody / PHOX2B
Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for the formation of autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2) .
Product Specifications
UniProt
Q99453
Reactivity
Human
Immunogen
A recombinant fragment of human protein was used as the immunogen for the Paired-like homeobox 2B antibody.
Clonality
Recombinant
Clone
PHOX2B/7792R
Conjugation
Unconjugated
Field of Research
Neuroscience; Stem Cell & Developmental Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the Paired-like homeobox 2B antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa
Frequently Asked Questions
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