AKT-IN-1
AKT-IN-1 is an allosteric AKT inhibitor with an IC50 of 1.042 μM.
Product Specifications
CAS Number
[1357158-81-6]
UNSPSC
12352005
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AKT-IN-1.html
Purity
98.41
Solubility
DMSO : 75 mg/mL (ultrasonic)
Smiles
NC(C1=CN=C(C2=CC=C(C3(N)CCC3)C=C2)C(C4=CC=CC=C4)=C1)=O
Molecular Formula
C22H21N3O
Molecular Weight
343.42
References & Citations
[1]Kettle JG, et al. Diverse heterocyclic scaffolds as allosteric inhibitors of AKT. J Med Chem. 2012 Feb 9;55 (3) :1261-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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