ER alpha Antibody / Estrogen Receptor alpha
This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. Epitope of this mAb is mapped between amino acids 495-595 of E/F domain. Estrogen Receptor is an important regulator of growth and differentiation in the mammary gland. Presence of Estrogen Receptor in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Product Specifications
UniProt
P03372
Reactivity
Human
Immunogen
Clonality
Monoclonal
Clone
AER311
Conjugation
Unconjugated
Purification
Protein A/G affinity
Dilution
Flow cytometry: 0.5-1ug/million cells, Immunofluorescence: 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the ER alpha antibody should be determined by the researcher.
Tested Applications
FACS, IF
Host or Source
Mouse
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Mouse IgG2a, kappa
Frequently Asked Questions
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