Alkyne-cRGD

Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction[1].

Product Specifications

CAS Number

[2665674-77-9]

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer; Others

Assay Protocol

https://www.medchemexpress.com/alkyne-crgd.html

Purity

99.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CCCC#C)=O)[C@H]1CC2=CC=C(C=C2)O

Molecular Formula

C33H47N9O9

Molecular Weight

713.78

References & Citations

[1]Zheng J, et al. Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation. J Am Chem Soc. 2022 Dec 7;144 (48) :21831-21836.