Alkyne-cRGD
Alkyne-cRGD is an integrin ligand. Alkyne-cRGD can be used in the study of degraders. Alkyne-cRGD undergoes copper-catalyzed azide-alkyne cycloaddition reaction[1].
Product Specifications
CAS Number
[2665674-77-9]
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer; Others
Assay Protocol
https://www.medchemexpress.com/alkyne-crgd.html
Purity
99.48
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CCCC#C)=O)[C@H]1CC2=CC=C(C=C2)O
Molecular Formula
C33H47N9O9
Molecular Weight
713.78
References & Citations
[1]Zheng J, et al. Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation. J Am Chem Soc. 2022 Dec 7;144 (48) :21831-21836.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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