SAR 97276
SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC) . SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier[1].
Product Specifications
CAS Number
[321915-72-4]
Product Name Alternative
Albitiazolium (bromide)
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sar-97276.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCC1=C(C)[N+](CCCCCCCCCCCC[N+]2=CSC(CCO)=C2C)=CS1.[Br-].[Br-]
Molecular Formula
C24H42Br2N2O2S2
Molecular Weight
614.54
References & Citations
[1]Wein S, et al., Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate. Br J Pharmacol. 2012 Aug;166 (8) :2263-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Human Coiled-coil domain-containing protein 125 (CCDC125) ELISA Kit
Recombinant Sudan ebolavirus Envelope glycoprotein (GP), partial
Recombinant Sudan ebolavirus Envelope glycoprotein (GP), partial
Recombinant Sudan ebolavirus Envelope glycoprotein (GP), partial
Recombinant Sudan ebolavirus Envelope glycoprotein (GP), partial