SAR 97276
SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC) . SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier[1].
Product Specifications
CAS Number
[321915-72-4]
Product Name Alternative
Albitiazolium (bromide)
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sar-97276.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCCC1=C(C)[N+](CCCCCCCCCCCC[N+]2=CSC(CCO)=C2C)=CS1.[Br-].[Br-]
Molecular Formula
C24H42Br2N2O2S2
Molecular Weight
614.54
References & Citations
[1]Wein S, et al., Transport and pharmacodynamics of albitiazolium, an antimalarial drug candidate. Br J Pharmacol. 2012 Aug;166 (8) :2263-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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