Purified Anti-Human CD123 Monoclonal Antibody
Product Specifications
Background
CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
CAS Number
9007-83-4
Synonyms
IL-3Rα, IL-3 Receptor alpha
Swiss Prot
[object Object]
Host
Mouse
Reactivity
Human
Conjugation
Unconjugated
Applications
FCM, WB, IHC, IP
Concentration
0.2 mg/mL
Buffer
PBS with 0.05% Proclin300
Storage Conditions
Store at 2~8°C. Do not freeze.
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