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Purified Anti-Human CD54 Monoclonal Antibody

Product Specifications

Background

CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.

CAS Number

9007-83-4

Synonyms

Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54, Icam-1

Swiss Prot

[object Object]

Host

Mouse

Reactivity

Human

Conjugation

Unconjugated

Applications

FCM, WB, IHC

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300

Storage Conditions

Store at 2~8°C. Do not freeze.

Available Sizes

Frequently Asked Questions

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