AF/LE Purified Anti-Mouse CD117 Antibody

Product Specifications

Background

CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR) . It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor) . CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

CAS Number

9007-83-4

Synonyms

Mast/stem cell growth factor receptor Kit, Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117

Gene ID

16590

Swiss Prot

P05532

Host

Rat

Reactivity

Mouse

Isotype

IgG2b κ

Conjugation

None (Purified antibody-Azide Free/Low endotoxin)

Applications

FCM

Concentration

0.5 mg/mL

Buffer

0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.