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AF/LE Purified Anti-Mouse CD132 Antibody

Product Specifications

Background

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID) .

CAS Number

9007-83-4

Synonyms

Cytokine receptor common subunit gamma, Il2rg, Interleukin-2 receptor subunit gamma, IL-2 receptor subunit gamma, IL-2R subunit gamma, IL-2RG, gammaC, p64, CD132

Gene ID

16186

Swiss Prot

P34902

Host

Rat

Reactivity

Mouse

Isotype

IgG2b κ

Conjugation

None (Purified antibody-Azide Free/Low endotoxin)

Applications

FCM

Concentration

0.5 mg/mL

Buffer

0.2 μm filtered in PBS, pH7.2. Azide Free (AF) /Low Endotoxin (LE) : Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Storage Conditions

Store at 2~8°C. Do not freeze.

Available Sizes

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