Human Factor IXa Affinity Fluorescein-INFPR Labeled

<strong>Human Factor IXa Affinity Fluorescein-INFPR Labeled</strong>_x000D_ <strong>Catalog number:</strong> B2017472_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80¬∞C_x000D_ <strong>Keywords:</strong> N/A_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Larson PJ, Stanfield-Oakley SA, VanDusen WJ, Kasper CK, Smith KJ, Monroe DM, High KA. Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa J Biol Chem. 1996 Feb 16;271(7):3869-76._x000D_ 2: Burnouf T, Michalski C, Goudemand M, Huart JJ. Properties of a highly purified human plasma factor IX:c therapeutic concentrate prepared by conventional chromatography Vox Sang. 1989;57(4):225-32._x000D_ 3: Jenkins PV, Dill JL, Zhou Q, Fay PJ. Contribution of factor VIIIa A2 and A3-C1-C2 subunits to the affinity for factor IXa in factor Xase Biochemistry. 2004 May 4;43(17):5094-101._x000D_ 4: Nagase H, Enjyoji K, Minamiguchi K, Kitazato KT, Kitazato K, Saito H, Kato H. Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin Blood. 1995 Mar 15;85(6):1527-34._x000D_ 5: Lenting PJ, Christophe OD, Maat H, Rees DJ, Mertens K. Ca2+ binding to the first epidermal growth factor-like domain of human blood coagulation factor IX promotes enzyme activity and factor VIII light chain binding J Biol Chem. 1996 Oct 11;271(41):25332-7._x000D_ 6: McCord DM, Monroe DM, Smith KJ, Roberts HR. Characterization of the functional defect in factor IX Alabama. Evidence for a conformational change due to high affinity calcium binding in the first epidermal growth factor domain J Biol Chem. 1990 Jun 25;265(18):10250-4._x000D_ 7: Lenting PJ, ter Maat H, Clijsters PP, Donath MJ, van Mourik JA, Mertens K. Cleavage at arginine 145 in human blood coagulation factor IX converts the zymogen into a factor VIII binding enzyme J Biol Chem. 1995 Jun 23;270(25):14884-90._x000D_ 8: Buyue Y, Sheehan JP. Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exosite Blood. 2009 Oct 1;114(14):3092-100._x000D_ 9: Neuenschwander P, Jesty J. A comparison of phospholipid and platelets in the activation of human factor VIII by thrombin and factor Xa, and in the activation of factor X Blood. 1988 Nov;72(5):1761-70._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/1989995">10: Astermark J, Stenflo J. The epidermal growth factor-like domains of factor IX. Effect on blood clotting and endothelial cell binding of a fragment containing the epidermal growth factor-like domains linked to the gamma-carboxyglutamic acid region J Biol Chem. 1991 Feb 5;266(4):2438-43.</a>_x000D_ _x000D_ <strong>Products Related to Human Factor IXa Affinity Fluorescein-INFPR Labeled can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>