APC Anti-Human CD183/CXCR3 Antibody
Product Specifications
Background
Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.
CAS Number
9007-83-4
Synonyms
CXCR3, GPR9, CXC-R3, CXCR-3, CKR-L2
Gene ID
2833
Swiss Prot
P49682
Host
Mouse
Reactivity
Human
Isotype
IgG1 κ
Conjugation
APC
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
Curated Selection
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