AF488 Anti-Human CD81 Antibody
Product Specifications
Background
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody) . CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
CAS Number
9007-83-4
Synonyms
CD81 antigen, CD81,26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1.Tetraspanin-28, Tspan-28, APA1, TSPAN28
Gene ID
975
Swiss Prot
P60033
Host
Mouse
Reactivity
Human
Isotype
IgG1 κ
Conjugation
AF488
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
Frequently Asked Questions
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