AF647 Anti-Human CD11b Antibody
Product Specifications
Background
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2 (CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
CAS Number
9007-83-4
Synonyms
Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Gene ID
3684
Swiss Prot
P11215
Host
Mouse
Reactivity
Human
Isotype
IgG1 κ
Conjugation
AF647
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
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