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AF488 Anti-Human CD123 Antibody

Product Specifications

Background

CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

CAS Number

9007-83-4

Synonyms

IL-3Rα, IL-3 Receptor alpha

Gene ID

3563

Swiss Prot

P26951

Host

Mouse

Reactivity

Human

Isotype

IgG1 κ

Conjugation

AF488

Applications

FCM

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Available Sizes

Frequently Asked Questions

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