PE Anti-Mouse IL-10 Antibody

Product Specifications

Background

L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production) ; and promotes mast cell proliferation in combination with IL-4.

CAS Number

9007-83-4

Synonyms

Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF

Gene ID

16153

Swiss Prot

P18893

Host

Rat

Reactivity

Mouse

Isotype

IgG2b κ

Conjugation

Applications

ICFCM

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.