Purified Anti-Mouse CD209b Antibody
Product Specifications
Background
CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.
CAS Number
9007-83-4
Synonyms
CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b
Gene ID
69165
Swiss Prot
Q8CJ91
Host
Armenian Hamster
Reactivity
Mouse
Isotype
IgG
Conjugation
Unconjugated
Applications
FCM
Concentration
0.5 mg/mL
Buffer
PBS with 0.05% Proclin300
Storage Conditions
Store at 2~8°C. Do not freeze.
Available Sizes
Frequently Asked Questions
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