AF488 Anti-Human CD11a Antibody

Product Specifications

Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .

Synonyms

Integrin alpha-L, Itgal, CD11 antigen-like family member A, LFA-1A, Lymphocyte antigen 15, Ly-15, CD11a

Gene ID

3683

Swiss Prot

P20701

Host

Mouse

Reactivity

Human

Isotype

IgG1 κ

Conjugation

AF488

Applications

FCM

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

CAS Number

9007-83-4

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