AF488 Anti-Human CD11a Antibody
Product Specifications
Background
CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50) .
CAS Number
9007-83-4
Synonyms
Integrin alpha-L, Itgal, CD11 antigen-like family member A, LFA-1A, Lymphocyte antigen 15, Ly-15, CD11a
Gene ID
3683
Swiss Prot
P20701
Host
Mouse
Reactivity
Human
Isotype
IgG1 κ
Conjugation
AF488
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
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