AF488 Anti-Human CD45RA Antibody
Product Specifications
Background
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
CAS Number
9007-83-4
Synonyms
Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45
Gene ID
5788
Swiss Prot
P08575
Host
Mouse
Reactivity
Human
Isotype
IgG2b κ
Conjugation
AF488
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
144504 100 µg
FADD (FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity)
Sign In for Pricing
View Details USP1205 500 mL
Reagecon Bromate-Bromide 0.100N according to United States Pharmacopoeia (USP)
Sign In for Pricing
View Details 
MBS7070195 Inquire
Recombinant Bacillus subtilis Sporulation-killing factor biosynthesis protein skfC (skfC), partial
Sign In for Pricing
View Details