(Rac) -Tipifarnib
(Rac) -Tipifarnib ((Rac) -IND 58359; (Rac) -R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac) -Tipifarnib showed significant in vivo antitumor effects after oral administration to mice[1].
Product Specifications
CAS Number
192185-68-5
Product Name Alternative
(Rac) -IND 58359; (Rac) -R115777
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac-tipifarnib.html
Smiles
O=C1N(C2=C(C(C3=CC=CC(Cl)=C3)=C1)C=C(C=C2)C(N)(C4=CN=CN4C)C5=CC=C(C=C5)Cl)C
Molecular Formula
C27H22Cl2N4O
Molecular Weight
489.40
References & Citations
[1]Venet M, et al. Farnesyl protein transferase inhibitor ZARNESTRA™ R115777-History of a discovery[J]. Current Topics in Medicinal Chemistry, 2003, 3 (10) : 1095-1102.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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