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APC Anti-Mouse CD45.1 Antibody

Product Specifications

Background

CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA) . CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

CAS Number

9007-83-4

Synonyms

Ly-5, L-CA, T200, CD45, Ptprc

Gene ID

19264

Host

Mouse

Reactivity

Mouse

Isotype

IgG2a κ

Conjugation

APC

Applications

FCM

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Available Sizes

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