21-Hydroxyoligomycin A
Product Specifications
UNSPSC Description
21-Hydroxyoligomycin A is a potent inhibitor of K-Ras PM localization with an IC50 value of 4.82 nM. 21-Hydroxyoligomycin A has cytotoxicity and can be isolated from Streptomyces[1].
Target Antigen
Antibiotic; Ras
Type
Natural Products
Related Pathways
Anti-infection;GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/21-hydroxyoligomycin-a.html
Solubility
10 mM in DMSO
Smiles
C[C@@H]([C@]1([H])OC(/C=C/[C@@H]([C@H]([C@@H](C([C@@H]([C@H]([C@@H]2C)O)C)=O)C)O)C)=O)[C@@](O[C@H]3C[C@H](O)C)(CC[C@@H]3C)O[C@](C[C@H]([C@H](/C=C/C=C\C[C@H]([C@@H]([C@@](O)(C2=O)C)O)C)CC)O)([H])[C@H]1C
Molecular Weight
807.06
References & Citations
[1]Salim AA, et al. Oligomycins as inhibitors of K-Ras plasma membrane localisation. Org Biomol Chem. 2016 Jan 14;14(2):711-715.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112541/21-Hydroxyoligomycin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112541/
Clinical Information
No Development Reported
CAS Number
102042-09-1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
