AZ-Dyrk1B-33
AZ-Dyrk1B-33 is a potent and selective Dyrk1B kinase inhibitor, with an IC50 of 7 nM[1].
Product Specifications
CAS Number
1679330-37-0
Product Name Alternative
(±)-Pirmenol (hydrochloride); CI-845,(±)-Pirmenol; CI-845 (free base)
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DYRK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/az-dyrk1b-33.html
Purity
99.95
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC1=NC=CC(C2=CN(CC3=CC=CC=C3)C4=C2C=CN=C4)=N1
Molecular Formula
C19H16N4
Molecular Weight
300.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Kettle JG, et al. Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. J Med Chem. 2015 Mar 26;58 (6) :2834-44.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH030698 50 µg
Recombinant Human SerpinB3/SCCA1 Protein (His Tag)
Sign In for Pricing
View Details 
GAF-551-15 1 mL
Colloidal Gold Conjugated Rabbit Affinity Purified Antibody to Sheep IgG, 15nm
Sign In for Pricing
View Details 
LY402330 100 µg
Bcl2 Binding component 3 (BBC3) (NM_014417) Human Over-expression Lysate
Sign In for Pricing
View Details