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APC Anti-Mouse CD90.2 Antibody

Product Specifications

Background

CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-) . CD90.2 is a glycosylphosphatidylinositol (GPI) -anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.

CAS Number

9007-83-4

Synonyms

Thy-1.2 membrane glycoprotein, Thy1.2, Thy-1.2 antigen, CD90.2, Thy-1.2

Gene ID

21838

Host

Rat

Reactivity

Mouse

Isotype

IgG2b κ

Conjugation

APC

Applications

FCM

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Available Sizes

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