Purified Anti-Human CD7 Antibody

Product Specifications

Background

CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly) . CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

CAS Number

9007-83-4

Synonyms

T-cell antigen CD7, CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, TP41

Gene ID

924

Swiss Prot

P09564

Host

Mouse

Reactivity

Human

Isotype

IgG1 κ

Conjugation

Unconjugated

Applications

FCM

Concentration

0.5 mg/mL

Buffer

PBS with 0.05% Proclin300

Storage Conditions

Store at 2~8°C. Do not freeze.