FITC Anti-Human CD45RA Antibody
Product Specifications
Background
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
CAS Number
9007-83-4
Synonyms
Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45
Gene ID
5788
Swiss Prot
P08575
Host
Mouse
Reactivity
Human
Isotype
IgG2b κ
Conjugation
FITC
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
