AF488 Anti-Mouse CD161/NK1.1 Antibody
Product Specifications
Background
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
CAS Number
9007-83-4
Synonyms
Killer cell lectin-like receptor subfamily B member 1C, Klrb1c, CD161 antigen-like family member C, Ly-55c, CD161/NK1.1, NKR-P1.9, NKR-P1C, NKR-P1 40, CD161c
Gene ID
17059
Swiss Prot
P27814, P27812, Q99JB4
Host
Mouse
Reactivity
Mouse
Isotype
IgG2a κ
Conjugation
AF488
Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Conditions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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